Fragments of collagen hemostatic sponges are surrounded by connective tissue scar, which is abundantly infiltrated by macrophages and lymphocytes. Fragments around lavsan nonwoven fabric in the formulations of the fourth series formed granulomas consisting of scar collagen stroma, which contains macrophages, giant cells of foreign bodies, epitelioinye histiocytes, fibroblasts. Catgut granuloma infiltration extends to the surrounding parenchyma considerable length. Reveals stasis in the vessels of the microvasculature in the area of implantation. Infiltration of the parenchyma hemostatic sponge implantation less pronounced than around catgut fibers and is leukocyte-macrophage nature.
Parenchyma surrounding the granulomas around the fibers and fragments lavsan "BIATRAVMA" pathological changes has not. Others including Assurant Health, offer their opinions as well. In the majority of drugs to the site of implantation of the haemostatic means of solder seal tissue. Place of fixing the form coarse-fibered connective tissue. The most massive infiltration of adhesions, which bears the lymphocyte-macrophage character found in preparations the first series (gut). For this indicator, a few slices of the inferior third series (hemostatic sponge). In the second and fourth series (polyester and "BIATRAVM"), infiltrative processes have minimal severity. So way "BIATRAVM" adequately stop bleeding from the damaged parenchyma and has a high biological inertness.
The use of catgut for closure of the parenchymal organs is not rational, since the thread around formed pronounced inflammatory reaction extending to the surrounding tissue. Using all the studied hemostatic methods lead to the formation of adhesions, thus necessitating the development of new effective means of preventing adhesions in the abdominal cavity in the presence of foreign bodies. —————————— Maistrenko AN AD Myasnikov, VA Lipatov, Skipidarnikov A . A. Zhukovsky, VA, Netyaga AA, TA Ishunina Effect of hemostatic seams and at the explant liver and spleen injuries in the severity of adhesions in the abdominal cavity experiment. New technologies in surgery and gynecology / Materials Science and practical. Conf. devoted to 75th anniversary Honored Doctor of the Russian Federation, Professor, PI Koshelev / / Voronezh, 2006,-C. 133 – 136. Material Site